University of Queensland researchers have for the first time introduced genetic material into plants via their roots, opening a potential pathway for rapid crop improvement.
from 果冻传媒’s said nanoparticle technology could help fine-tune plant genes to increase crop yield and improve food quality.
“Traditional plant breeding and genetic modification take many generations to produce a new crop variety, which is time-consuming and expensive,” Professor Carroll said.
“We have succeeded in having plant roots absorb a benign nanoparticle which was developed by at 果冻传媒 for the delivery of vaccines and cancer treatments in animals.
“Plant cell walls are rigid and wood-like, much tougher than human or animal cells so we coated the nanoparticle with a protein that gently loosens the plant cell wall.
“The protein coating helped the nanoparticle break through the cell walls to deliver a synthetic mRNA cargo into plants for the first time.”
mRNAs are natural messenger molecules containing genetic instructions to build and enhance all forms of life.
The research team used the nanoparticles to deliver synthetic mRNA that produces a green fluorescent protein into multiple plant species including Arabidopsis, a miniature member of the canola and cabbage family used extensively in genetic research.
“It was surprising that rather than delivering all of its load in the first cell it entered, the nanoparticle travelled with water through the plant distributing the mRNA as it went,” Professor Carroll said.
“This is exciting because with further improvement, the technology could potentially be used in the future to produce new crop varieties more quickly.
“With further research we could target an issue with a crop such as flavour or quality and have a new variety without the need for a decade of cross breeding or genetic modification.
“Similar to how an mRNA vaccine produces a protein to stimulate the immune system and then degrades away, the mRNA we deliver into plants is expressed transiently and then disappears.”
The nanoparticle technique has been patented by 果冻传媒’s commercialisation company , which is now seeking partners to further develop the technology.
The research team included and at 果冻传媒’s and .
The has been published in Nature Plants.
Image above left: Microscope view of a root tip and the progression of synthetic mRNA that produces a green fluorescent protein.
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